Ergonomics are vital for anyone who works on a computer or laptop. The unfortunate truth is that you can’t spend a full workday using most mice without feeling the effects later. Enter ergonomic mice: the solution to your wrist cramping, finger-numbing desktop navigation challenges.
From everyday point-and-click to ultra-responsive gaming mice, we have recommendations for the best ergonomic mouse for your needs. In no time, you’ll be enjoying a more neutral mouse experience—and hopefully, less wrist pain.
At a glance
- Best gaming mouse overall: Logitech MX Vertical
- Best gaming mouse overall: Logitech MX Master 2S
- Best budget gaming mouse: Anker Wireless Vertical
- Best wireless gaming mouse: Microsoft Sculpt
- Best ambidextrous gaming mouse: Razer DeathAdder Elite
Logitech MX Vertical
Building off of developments in its other ergonomic mice, Logitech’s MX Vertical is the company’s first real attempt at a tall mouse that tackles the problems commonly associated with long-term mousing discomfort. Logitech claims it can offer up to a 10 percent reduction in muscle strain with extended usage. While that sort of metric is hard to accurately test, we did find it supremely comfortable during our testing. Better yet, it’s intuitive and easy to get to grips with.
With a hefty, but not overblown tilt angle of 57 degrees, the MX Vertical remains functional as an everyday mouse, while still providing the benefits of a more ergonomic peripheral. Its natural wrist positioning forces you to rest your hand in a position that is more conducive to long-term wrist health.
On top of all of its ergonomic features, this mouse actually looks good, too. Its combination of rubber and aluminum gives it a premium finish and feel, that for $100, feels well worth it to enjoy the benefits of ergonomic mousing. With wired and wireless options over Bluetooth (up to four months of battery life) and USB, it should work fine while you’re on the move or when tethered to a desk. Despite stiff competition, the MX Vertical steams ahead as the best ergonomic mouse you can buy today.
Logitech MX Master 2S
The true purpose of an ergonomic mouse is to provide comfortable, full-hand support for the user and encourage good forearm posture while providing a solid input option for traditional computing tasks. With an expansive thumb rest and design that cushions and molds to the palm, the MX Master 2S is a supremely comfortable and functional mouse.
The MX Master 2S sports a sensitivity of 4,000 DPI and its wireless battery life of 70 days means you don’t need to continually worry about recharging the battery. With a great blend of features and comfort, it’s a fully-featured ergonomic mousing solution.
Exclusively available for right-hand users, the hand-sculpted design of the MX Master 2S is specially made to keep your wrist in as neutral position as possible in the horizontal orientation. It uses a laser sensor (rather than optical) so it can track on any surface, recharges quickly (three minutes gives you a day of juice), and it can be paired over Bluetooth with up to three different devices.
Anker Wireless Vertical
Your wrists don’t care how expensive an ergonomic mouse is, which can be a problem for those who don’t want to spend a lot of cash on a mouse replacement. Fortunately, Anker’s solution is a great vertical ergonomic model that’s as affordable a mouse as you can find. It offers options for 800, 1200 or 1600 DPI optical tracking that you can switch between to find the sensitivity that you like, and includes built in previous/next buttons for easy browsing — although they, like all five buttons on the mouse, can be mapped to different commands if you prefer.
While the mouse runs on two AAA batteries, it does help conserve battery life with a power saving mode that it will enter after eight minutes without use. While we’re fans of the design and the price is amazing, we should note that this mouse is a bit large. If you have especially small hands, it might prove difficult to use. It’s also right-handed only.
Taking a much more minimalist approach to ergonomic mouse design, Microsoft’s Sculpt mouse is a rounded blob that’s designed to offer solid palm support without any extraneous features. It has a thumb rest to cushion your thumb into the side of the mouse, but it’s bulbous design, as we called it, is intended to teach you to lift your wrist off of your mat or desk when using it — encouraging the use of forearm muscles, rather than wrist tendons, to support your hand.
Effectively, the Sculpt aims to have you do the hard work of supporting your wrist and mousing hand yourself, rather than acting as an overall supportive tool for you.
The Sculpt has the usual pair of left/right-click buttons and a central scroll wheel that can move in four directions. It also has a side-mounted “Windows” button which gives Windows users quick access to the Start menu, and a secret “back” button hidden near the rear of the mouse for faster browser navigation.
This wireless mouse is powered by just two AA batteries and connects up to your PC using an included 2.4GHz USB dongle. If you really don’t like the shape of this mouse but do like its other features, Microsoft also has a “comfort” mouse with a more traditional shape that you might like.
Razer DeathAdder Elite
Many gaming mice use ambidextrous designs that are more catered to claw or finger-grip mouse styles, but there are a number that also offer good ergonomic support and the Razer DeathAdder Elite is one of them. One of the best mice we have ever reviewed, it offers amazing features for gamers, while still providing decent support for your wrist and hand, no matter your grip style.
With the classic DeathAdder look and feel, this mouse features a subtly shaped body to offer decent wrist support during long gaming sessions. Although it doesn’t have a rest for your thumb, it does have an indentation for you to grip with and there is plenty of shelf space for your fingers on the other side.
By virtue of being a gaming mouse first, this rodent has arguably the best specifications of all of the mice on this list. It sports a true 16,000 DPI optical sensor, with mechanical switches for long-life and support for Razer’s Chroma RGB lighting system. It also supports Razer’s powerful back-end software for key remapping and color customization.
Unlike many of the best ergonomic mice, Razer also produces a left-handed version of its DeathAdder Elite, too.
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