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CBD oil for pain management: Best companies 2021

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This article is sponsored by Smart Media Inc.

CBD oil has become increasingly popular over the past couple of years as a promising remedy for multiple health issues, including pain management. Many using medical marijuana have reported relief from chronic pain without the intoxicating effects.

Cannabidiol (CBD) oils contain low tetrahydrocannabinol elements derived from Cannabis sativa. It is one of the many cannabinoids present in the cannabis plant. Since its discovery, there has been a growing amount of preclinical and clinical evidence to support the use of CBD oils for various conditions, particularly for people experiencing chronic pain. It’s a solid alternative for addictive opioids, which are often used for pain relief.

Many CBD-based products have quickly come to market, including oils, tinctures, balms, and candy, but it’s important to remain cautious when using CBD products because there is still little regulation within the industry at large. Studies have found unsettling evidence of inaccurate labeling of tetrahydrocannabinol oils.

This article provides an overview of cannabinoids, CBD, and hemp oil designed to relieve chronic pain, outlines their benefits and some of the higher-quality, over-the-counter products recommended by clinicians.

Endogenous Cannabinoids Versus Exogenous Cannabinoids

Our bodies produce cannabinoid receptors, which contain naturally occurring cannabinoids that make up the endocannabinoid system, or ECS. The endocannabinoid system has highly complex cell signaling pathways within the central nervous system and immune system. When using CBD oils and other cannabinoid-based products they attempt to link to these receptors throughout the body.

There are two types of cannabinoids – endogenous cannabinoids and exogenous cannabinoids.

The body produces naturally occurring lipids, otherwise known as endogenous cannabinoids.

Exogenous cannabinoids, however, are not produced by the body. These are compounds found solely within cannabis plants and comes in a few varying forms, including:

  • CBD
  • Cannabichromene (CBC)
  • Cannabigerol (CBG
  • Tetrahydrocannabinol (THC)

Is CBD Effective For Pain Management?

Both endogenous and exogenous cannabinoids will bind to the receptors on your cells. Once this binding process begins, your cells will start to respond, stimulating a response that influences pain signaling pathways.

It’s important to note that CBD does not do as good a job of binding to your receptors as your natural lipids will. But, it will interact with neurological receptors found in the spinal cord. This will help to suppress chronic inflammatory pain.

This benefit has been tested and proven in this cannabinoid study, for example, which showed that CBD suppresses chronic inflammatory pain in mice. This occurred as protein levels within spinal glycine receptors significantly increased, which, in turn, helped with inflammatory-based pain.

CBD may also improve the effects of endogenous cannabinoids, which in turn helps to reduce pain. This 2018 study showed that kidney transplant patients with chronic pain experienced much relief when taking CBD. Interestingly, the study showed that participants who were given a higher dose of CBD felt more pain, and lower CBD doses resulted in the most effective pain control.

Using CBD For Pain Management

CBD products come in many forms, including:

  • Oils and tinctures
  • Capsules and oils
  • Topical patches
  • Creams and balms
  • Candy

CBD oils and tinctures are the most versatile products by far. They come in a dropper and can be added to a variety of different things, like lotion, food, drinks, etc.

What’s the Difference Between CBD and Hemp Extract?

You may hear CBD and hemp extract used interchangeably, but they are two different things. Though part of the same source, hemp extract stems from the hemp plant, but in a concentrated form. While in this form it maintains all the benefits within the plant itself. CBD is a single component of the hemp plant, known as the phytocannabinoid. Hemp is naturally high in phytocannabinoids. Because of this, many CBD products will utilize hemp extract in their formulas.

Best CBD Oils For Pain Management

  1. Charlotte’s Web 60 mg CBD Oil
  2. Smile Unwind CBD Oil
  3. Bloom Essential Recovery Tincture
  4. CBD American Shaman Water Soluble
  5. CBDFX CBD + CBG Oil Wellness Tincture
  6. Receptra Naturals Serious Relief
  7. Sunday Scaries CBD Oil Tincture
  8. Medterra CBD Oil

Charlotte’s Web 60 mg CBD Oil

Price: $119.99

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This is a full-spectrum CBD oil that comes from a well-trusted brand within the CBD community. Charlotte’s Web CBD products use US-based hemp plants that are grown in Colorado. This 60 mg oil is the highest concentration CBD per mL offered by the company. It also comes in 50 mg and 17 mg CBD formulas.

The higher dose is ideal for those who are already accustomed to CBD and looking to improve their supplement routine. The ingredients include full-spectrum hemp extract, along with naturally occurring phytocannabinoids, terpenes, and flavonoids. The benefits behind this ingredient list are designed to maintain calmness, reduce exercise-induced inflammation, and balance sleep patterns.

Each ingredient is carefully selected, with little fluff within the formulation. Essentially, there’s hemp extract, carrier oil, and a little bit of flavor. That’s it.

To stabilize such a high concentration of CBD, Charlotte’s Web uses a CO2 extraction method. This extraction agent, otherwise known as carbon dioxide, leaves no negative footprint on the environment.

Smile Unwind CBD Oil

Price: $42.50

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This product is formulated to promote calmness, reduce stress, support better sleep, and help relieve physical pain. It’s made with 100% organic CBD isolate, 5-HTP, hemp seed oil, MCT coconut oil, melatonin, ginseng, omega-3, omega-6, and omega-9.

Pure CBD will provide a calming effect, while ginseng is great for mental clarity. 5-HTP is a chemical by-product of the protein building block L-tryptophan, found in the Griffonia simplicifolia plant. It has been shown to increase the production of serotonin in the brain, ultimately helping with depression and anxiety.

The benefits of this product go beyond specifically pain management, but also helps to relieve stress and improve mood. Still, the cannabinoids found within this CBD oil have anti-inflammatory properties to help support recovery and alleviate joint pain due to swelling. It has antispasmodic properties, which can reduce the frequency and extent of muscle spasms. Overall, it’s a great CBD oil for pain.

Bloom Essential Recovery Tincture

Price: $79.99

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This recovery tincture contains turmeric, ginger, black seed, and hemp extract. Each individually is a powerful anti-inflammatory ingredient on its own. When combined, however, they create a super elixir that helps fight pain.

The theory behind blending turmeric, ginger, and black seed (black cumin seed) has been used for centuries, specifically in Ayurvedic medicine (an alternative medicine, holistic healing system practiced in India). The roots are smashed together, extracting the essential oils from the plants, to create a tea for people in need of relief.

This CBD oil abides by a similar approach, but with added Bioperine, which is a pepper extract that speeds up the effects of these ingredients to give faster relief.

Many hemp-derived CBD products are received with much skepticism. The benefits of CBD can only occur when the ingredient percentage is significant. Unfortunately, many CBD products are filled with unneeded fluff, making pain alleviation a rarity. Bloom, however, is backed by science. All the products are tested by a third-party lab to ensure the percentages are accurate before going to market.

CBD American Shaman Water Soluble, Full Spectrum Hemp Oil

Price: $14.99

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This is one of the more affordable options on the market. It may raise eyebrows on its effectiveness when sold at such a low price, but it does contain 10 mg CBD per 1 mL. The lower concentration of CBD extract explains the lower price point on this product.

This CBD oil is also rich in terpene. Cannabis terpene is not the same thing as cannabinoids, like CBD and THC. It is, however, extracted from the same glands that produce cannabinoids. Terpenes are aromatic oils that give cannabinoids distinct flavors, like mint, berry, and citrus.

The company creates CBD products from high-quality hemp plants grown throughout the U.S. They are planted on agriculturally-responsible farms that only use industry-standard extracting methods.

CBDFX CBD + CBG Oil Wellness Tincture

Price: $39.99

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This is a CBD oil tincture that’s 100% vegan, non-GMO, and extracted with CO2. It contains hemp oil, coconut oil (or MCT oil), Curcumin, Coenzyme Q10, CBG, CBN, and terpene blends.

The coconut oil is used as a carrier oil, helping to improve absorption of the CBD and deliver a consistent experience with every use. Curcumin and Coenzyme Q10 are known to have powerful antioxidant properties, increasing the effectiveness of the tincture. CBN is a type of cannabinoid that can aid with relaxation.

CBG, or cannabigerol, is another compound found in the cannabis plant that interacts with CB1 and CB2 receptors in the brain, providing further balance within the endocannabinoid system.

Receptra Naturals Serious Relief + Turmeric 0% THC Tincture

Price: $84.99

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This CBD oil is derived from hand-picked hemp flowers, using a cold ethanol extraction method. This method is also commonly used to derive vanilla.

This is a broad-spectrum tincture, formulated with a combination of pure and organic ingredients, proven to help with recovery and pain relief. It contains MCT oil, omega-3 and omega-6 fatty acids, turmeric, and avocado oil. These ingredients work together to provide a positive metabolic impact, faster recovery, and relief from aches and joint irritation.

Sunday Scaries CBD Oil Tincture

Price: $55

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This CBD oil is formulated with a high concentration of CBD, helping to boost calmness and reap the overall benefits this tincture has to offer. Every bottle holds a massive 500 mg of CBD, suspended with coconut oil. If you’re new to CBD, you may want to consider using something a bit milder when first starting.

It’s made with a proprietary blend of broad-spectrum CBD, vitamin B12, and vitamin D3. This combination of ingredients is designed to calm your mind and elevate your mood.

When dropped under your tongue, the oil will quickly absorb into your system. You can also choose to add it to a beverage, like water, tea, coffee, etc.

Medterra CBD Oil

Price: $34.99

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The Medterra CBD oil is derived from organically grown, industrial hemp. Every hemp plant is then tested by a third-party to guarantee the product is free of contaminants or other harsh additives. Then, the CBD is drawn out through a CO2 extraction process. This will allow any unnatural substances to be filtered out, ensuring a fully pure and organic CBD oil. This process is critical for yielding the highest quality oils within the hemp plant.

This CBD oil, specifically, is composed of 99% CBD and medium-chain triglyceride MCT oil, which is derived from coconuts. There are varying strengths available – 500 mg, 1,000 mg, and 3,000 mg. Each dosage is safe to use; it mostly depends on your preferences.

CBD Oil Alternatives

People who are experiencing continual and persistent pain, despite the use of CBD oil, may want to explore more alternatives with their physicians. Here are some options:

  • Physical therapy for stiff joints
  • Anti-inflammatory pain relievers
  • Massage
  • Acupuncture
  • Cortisone injection
  • Warm compress


While there is still much research and various clinical studies to be done within the Cannabidiol space, there is no denying the benefits of using CBD oil for pain. CBD products are generally safe to use, but there needs to be better regulation and scientific evidence for some of the over-the-counter products. If suffering from muscle, joint, or nerve pain, however, it can’t hurt to give high-quality CBD oil a chance.

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