The ultimate goal of getting an ergonomic mouse is to boost comfort by limiting unnecessary wrist movement. In choosing, consider the size and shape you will not mind adjusting to. Weight is another factor that some users claim helps anchor the hand. Also, think about the precision you need for daily processing tasks or gaming. Refer to our comprehensive guide to help you with this purchase.
Logitech MX Master 3
Best Overall
The Logitech MX Master 3 is horizontally shaped like your typical mouse, but it has additional features to support your hand. If you look a little closer, you’ll notice that its top is more curved than usual to raise your wrist slightly and provide a better mold to your palm. With your grip at an angular position, the risk of muscle cramps is decreased. It also has a convenient thumb rest and thumb wheel with customizable controls to help increase productivity.
The wireless mouse guarantees precision with a 4,000 DPI laser sensor that can work on any surface, including glass. Plus, it is equipped with a MagSpeed electro-magnetic wheel that lets you scroll up to 87 to 90% faster in a cinch without making noise. Battery life is hardly an issue since a full charge only requires three hours in exchange for up to 70-days of use. And if a minute is all you have, you’ll at least have enough juice for three hours of work.
Why we love it:
- Sculpted design lessens wrist strain
- Bluetooth pairing for multiple devices and operating systems
- USB-C capability facilitates fast charging
Anker Ergonomic Mouse
Best Value
Get the most bang for your buck with the Anker Wireless Ergonomic Optical Mouse. Safe to say, it ensures a pleasant and familiar grip at a reasonable price you’d be comfortable with. You’ll pretty much be shaking hands with your mouse to keep your wrist and arm at a neutral position for smoother and less straining movements.
Accurate navigation is achieved with Optical Tracking Technology, and you can even modify its sensitivity to 800, 1,200, or 1,600 DPI to match the surface you’re working on. Gamers and those who switch through countless tabs will appreciate the two side buttons dedicated to going back and forth web pages. It is powered by two AAA batteries and programmed to shut off automatically after eight idle minutes.
Why we love it:
- Five strategically placed buttons do not overextend fingers
- Energy-saving to preserve battery life
- Compatible with most operating systems
Logitech MX Ergo Mouse
Best Trackball
The Logitech MX Ergo Mouse enables your thumb to do all the tracking while your hand is completely at rest. Its rubber top is shaped like a paw to cradle your hand while your thumb gestures on its trackball. And to reduce muscle strain, you can tilt it to an angle of 0 to 20-degrees.
Since your hand hardly has to move, it will help save space and proves to be ideal for relatively small desktops. It can operate up to 2,048 DPI and navigate seamlessly and simultaneously across two computers. With Bluetooth pairing, you can use it with your personal computer, laptop, or tablet, be it Windows or Mac.
Why we love it:
- Cross-computer control for seamless navigation
- Personalized shortcuts for maximum efficiency
- One minute charge lasts an entire day
DELUX Ergo Mouse
Best Vertical 
The DELUX Ergo Mouse ensures a firm grip with a vertical design that can be likened to that of a joystick. As a result, arm discomfort and hand stiffness are reduced. Moreover, it has a detachable and padded wrist rest to elevate your wrist and protect it from friction.
It is a wired mouse that connects to a Windows laptop or desktop computer. You can adjust its DPI from 800 to 4,000 to make it more responsive on cloth, leather, wood, paper, or opaque glass. You will also not miss out on six programmable buttons, including forward and backward keys for web browsing.
Why we love it:
- Volute bionic design hinders forearm from twisting
- RGB lighting boosts computer aesthetics
- Five DPI selection increase sensitivity to decrease muscle fatigue
Corsair Nightsword Ergonomic Mouse
Best For Gaming
The Corsair Nightsword Ergonomic Mouse is one dependable gaming buddy that will not compromise your ability to make quick moves. It is wired, so you’ll have no issues with latency. Plus, it boasts an optical sensor of 18,000 DPI that is adjustable at 1 DPI resolutions steps for complete sensitivity customization. What’s more, it has ten programmable buttons to amp your play.
You can count on its silhouette and soft textured thumb rest to naturally fit in your hand. It is also integrated with Corsair-exclusive software to detect your mouse’s center of gravity and allow you to calibrate its weight to improve your balance and grip.
Why we love it:
- High-performance rubber grips make it great for long periods of use
- Two sets of weights offer 120 balance configurations
- High-speed motion detection up to 400 IPS ensures accurate tracking
Since most of us are used to a standard mouse, understand that there will be a learning curve as you transition to an ergonomic mouse. Its primary purpose is to reduce muscle tension in your grip and wrist that may progress to chronic pain or injury such as Carpal tunnel. Also, discern whether a wired or wireless mouse fits your lifestyle. Wireless is great on the go, but there is the probability of losing the USB receiver and may need battery replacements. Our curated list of the best ergonomic mice only aims to narrow down your search by presenting a variety that caters to most preferences.
About the Author
Rusty Davis has been a tech lover for as long as he can remember. From the early days of gaming consoles to the introduction of the smartphone, portable computers, and more, he’s always wanted to get his hands on the latest and greatest. He has years upon years of experience reviewing and testing everything from phone cases to smartwatches, the latest phones and tablets to gaming computers, and even desks. If it’s a piece of tech or tech-adjacent, he’s interested in how it works and who it works best for. He’s now here sharing all of his knowledge with you to help you make the best decision for yourself.
Why You Should Trust Us
The Digital Trends team prides itself in offering expert product recommendations in ways that everyone can understand. Our team of experts is constantly using and reviewing the latest and greatest consumer tech, smart home gadgets, televisions, and so much more to offer insights to help guide your purchasing decision. We have vigorously tested thousands of different products across these categories, and we’ve distilled our lists to bring you the best of the best. If we feel a product does not live up to our expectations, it doesn’t make the list. We are humans though, and realize that not every recommended product will be perfect for everyone, so we do our best to call out important features that may impact your choices. Below our top picks we’ve included additional product information to ensure that you are making the right choice for your unique needs.
The products in this guide have been carefully curated by our team of experts and enthusiasts who understand the value and quality needed for the best options.
